BOTOX® (onabotulinumtoxinA) Important Information. Please scroll for BOTOX® Important Safety Information including Boxed Warning, full Prescribing Information and Medication Guide.
IMPORTANT SAFETY INFORMATION and PRESCRIBING INFORMATION FOR
BOTOX® Cosmetic (onabotulinumtoxinA) , JUVÉDERM® Injectable Gel Fillers, KYBELLA® (deoxycholic acid) injection 10 mg/mL , CoolSculpting® Treatment, CoolTone® Treatment, Natrelle® Breast Implants including Boxed Warning, REVOLVE™ ADVANCED ADIPOSE SYSTEM, SkinMedica®, LATISSE® (bimatoprost ophthalmic solution) 0.03%
BOTOX® Cosmetic (onabotulinumtoxinA) Important Information
Approved Uses
BOTOX® Cosmetic is a prescription medicine that is injected into muscles and used to temporarily improve the look of moderate to severe forehead lines, crow’s feet lines, and frown lines between the eyebrows in adults.
IMPORTANT SAFETY INFORMATION
BOTOX® Cosmetic may cause serious side effects that can be life threatening. Get medical help right away if you have any of these problems any time (hours to weeks) after injection of BOTOX® Cosmetic:
- Problems swallowing, speaking, or breathing, due to weakening of associated muscles, can be severe and result in loss of life. You are at the highest risk if these problems are pre-existing before injection. Swallowing problems may last for several months.
- Spread of toxin effects. The effect of botulinum toxin may affect areas away from the injection site and cause serious symptoms including: loss of strength and all-over muscle weakness, double vision, blurred vision and drooping eyelids, hoarseness or change or loss of voice, trouble saying words clearly, loss of bladder control, trouble breathing, and trouble swallowing.
BOTOX® Cosmetic dosing units are not the same as, or comparable to, any other botulinum toxin product.
There has not been a confirmed serious case of spread of toxin effect when BOTOX® Cosmetic has been used at the recommended dose to treat frown lines, crow’s feet lines, and/or forehead lines.
BOTOX® Cosmetic may cause loss of strength or general muscle weakness, vision problems, or dizziness within hours to weeks of taking BOTOX® Cosmetic. If this happens, do not drive a car, operate machinery, or do other dangerous activities.
Serious and/or immediate allergic reactions have been reported. They include: itching, rash, red itchy welts, wheezing, asthma symptoms, or dizziness or feeling faint. Get medical help right away if you are wheezing or have asthma symptoms, or if you become dizzy or faint.
Do not receive BOTOX® Cosmetic if you: are allergic to any of the ingredients in BOTOX® Cosmetic (see Medication Guide for ingredients); had an allergic reaction to any other botulinum toxin product such as Myobloc® (rimabotulinumtoxinB), Dysport® (abobotulinumtoxinA), or Xeomin® (incobotulinumtoxinA); have a skin infection at the planned injection site.
Tell your doctor about all your muscle or nerve conditions, such as ALS or Lou Gehrig’s disease, myasthenia gravis, or Lambert-Eaton syndrome, as you may be at increased risk of serious side effects including difficulty swallowing and difficulty breathing from typical doses of BOTOX® Cosmetic.
Tell your doctor about all your medical conditions, including: plans to have surgery; had surgery on your face; have trouble raising your eyebrows; drooping eyelids; any other abnormal facial change; are pregnant or plan to become pregnant (it is not known if BOTOX® Cosmetic can harm your unborn baby); are breast-feeding or plan to (it is not known if BOTOX® Cosmetic passes into breast milk).
Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Using BOTOX® Cosmetic with certain other medicines may cause serious side effects. Do not start any new medicines until you have told your doctor that you have received BOTOX® Cosmetic in the past.
Tell your doctor if you have received any other botulinum toxin product in the last 4 months; have received injections of botulinum toxin such as Myobloc®, Dysport®, or Xeomin® in the past (tell your doctor exactly which product you received); have recently received an antibiotic by injection; take muscle relaxants; take an allergy or cold medicine; take a sleep medicine; take aspirin-like products or blood thinners.
Other side effects of BOTOX® Cosmetic include: dry mouth; discomfort or pain at the injection site; tiredness; headache; neck pain; and eye problems: double vision, blurred vision, decreased eyesight, drooping eyelids and eyebrows, swelling of your eyelids and dry eyes.
For more information refer to the Medication Guide or talk with your doctor.
To report a side effect, please call Allergan at 1-800-678-1605.
Please see BOTOX® Cosmetic full Product Information including Boxed Warning and Medication Guide.
JUVÉDERM® Injectable Gel FillersImportant Information
APPROVED USES
JUVÉDERM® VOLUMA® XC injectable gel is for deep injection in the cheek area to correct age-related volume loss and for augmentation of the chin region to improve the chin profile in adults over 21.
JUVÉDERM® VOLLURE® XC, JUVÉDERM® Ultra Plus XC, and JUVÉDERM® Ultra XC injectable gels are for injection into the facial tissue for the correction of moderate to severe facial wrinkles and folds, such as nasolabial folds. JUVÉDERM® VOLLURE® XC injectable gel is for adults over 21.
JUVÉDERM® Ultra XC injectable gel is also for injection into the lips and perioral area for lip augmentation in adults over 21.
JUVÉDERM® VOLBELLA® XC injectable gel is for injection into the lips for lip augmentation and correction of perioral lines, and for injection into the undereye hollows to improve the appearance of undereye hollows in adults over the age of 21.
IMPORTANT SAFETY INFORMATION
Are there any reasons why I should not receive any JUVÉDERM® formulation?
Do not use these products if you have a history of multiple severe allergies or severe allergic reactions (anaphylaxis), if you are allergic to lidocaine or the Gram-positive bacterial proteins used in these products, or if you have had previous allergic reactions to hyaluronic acid fillers.
What warnings should my doctor advise me about?
- One of the risks with using dermal fillers is the unintentional injection into a blood vessel. The chances of this happening are very small, but if it does happen, the complications can be serious and may be permanent. These complications, which have been reported for facial injections, can include vision abnormalities, blindness, stroke, temporary scabs, or permanent scarring of the skin
- The use of dermal fillers where skin sores, pimples, rashes, hives, cysts, or infections are present should be postponed, as this may delay healing or make skin problems worse
What precautions should my doctor advise me about?
- JUVÉDERM® VOLBELLA® XC should only be injected into undereye hollows by doctors who have completed the necessary training for this treatment area. To find a doctor, visit Juvederm.com/find-a-specialist. Doctors who complete the training will be listed with a symbol
- The safety of these products for use during pregnancy or while breastfeeding has not been studied
- The safety of JUVÉDERM® VOLUMA® XC has not been studied in patients under 35 years or over 65 years for cheek augmentation, or under 22 years and over 80 years for chin augmentation. The safety of JUVÉDERM® VOLLURE® XC and JUVÉDERM® VOLBELLA® XC has not been studied in patients under 22 years, and the safety of JUVÉDERM® Ultra Plus XC and JUVÉDERM® Ultra XC has not been studied in patients under 18 years
- The safety and effectiveness of treatment with JUVÉDERM® products in anatomical regions outside of their approved uses have not been established in clinical studies
- If you have a history of excessive scarring (thick, hard scars) or pigmentation disorders, treatment in these patients has not been studied and may result in additional scars or changes in pigmentation
- If you are planning other procedures including laser treatments or a chemical peel, there is a possible risk of inflammation at the treatment site if these procedures are performed closely before or after JUVÉDERM® injectable gel treatment
- Tell your doctor if you are on therapy used to reduce your body’s natural defense system (such as steroids, chemotherapy, and medicines to treat autoimmune diseases, HIV, and AIDs), as these may increase your risk of infection; and medications that can prolong bleeding (such as aspirin, ibuprofen, or other blood thinners), as these may result in increased bruising or bleeding at the injection site
- Minimize strenuous exercise, exposure to extensive sun or heat, and alcoholic beverages within the first 24 hours following treatment, as these may cause temporary redness, swelling, and/or itching at the injection site
- JUVÉDERM® VOLUMA® XC was not studied in patients with significant loose skin of the chin, neck, or jaw
- The effect of JUVÉDERM® VOLUMA® XC injection into the chin on facial hair growth has not been studied
- Patients who experience skin injury near the site of JUVÉDERM® VOLUMA® XC injection may be at a higher risk for adverse events
What are possible side effects of treatment?
The most commonly reported side effects with JUVÉDERM® injectable gels were redness, swelling, pain, tenderness, firmness, lumps/bumps, bruising, discoloration, and itching. For JUVÉDERM® VOLBELLA® XC, dryness was also reported.
These side effects are consistent with other facial injection procedures and most will resolve with time. Your doctor may choose to treat side effects persisting over 30 days with antibiotics, steroids, or hyaluronidase (an enzyme that breaks down hyaluronic acid).
As with all skin injection procedures, there is a risk of infection.
To report a side effect with any product in the JUVÉDERM® Collection, please call the Allergan® Product Support Department at 1-877-345-5372. Please also visit Juvederm.com or talk to your doctor for more information.
Products in the JUVÉDERM® Collection are available only by a licensed physician or properly licensed practitioner.
KYBELLA® (deoxycholic acid) injection 10 mg/mL Important Information
IMPORTANT SAFETY INFORMATION
What is KYBELLA®?KYBELLA® is a prescription medicine used in adults to improve the appearance and profile of moderate to severe fat below the chin (submental fat), also called “double chin.”
It is not known if KYBELLA® is safe and effective for the treatment of fat outside of the submental area or in children under 18 years of age.
Who should not receive KYBELLA®?
Do not receive KYBELLA® if you have an infection in the treatment area.
Before receiving KYBELLA®, tell your healthcare provider about all of your medical conditions, including if you: Have had or plan to have surgery on your face, neck, or chin; have had cosmetic treatments on your face, neck, or chin; have had or have medical conditions in or near the neck area; have had or have trouble swallowing; have bleeding problems; are pregnant or plan to become pregnant (it is not known if KYBELLA® will harm your unborn baby); are breastfeeding or plan to breastfeed (it is not known if KYBELLA® passes into your breast milk).
Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Especially tell your healthcare provider if you take a medicine that prevents the clotting of your blood (antiplatelet or anticoagulant medicine).
What are the possible side effects of KYBELLA®?
KYBELLA® can cause serious side effects, including
- Nerve injury in the jaw (which can cause an uneven smile or facial muscle weakness)
- Trouble swallowing
- Injection site problems including: a collection of blood under the skin (hematoma) or bruising, damage to an artery or vein if KYBELLA® is inadvertently injected into it, hair loss, open sores (ulcers), damage and tissue cell-death (necrosis) around the injection site. Call your healthcare provider if you: begin to develop weakness in the muscles of your face, or your smile becomes uneven; have difficulty swallowing, or if any of the symptoms that you already have get worse; develop open sores or drainage from the treatment area
The most common side effects of KYBELLA® include swelling, pain, numbness, redness, and areas of hardness in the treatment area.
These are not all of the possible side effects of KYBELLA®. Call your doctor for medical advice about side effects.
Please see KYBELLA® full Prescribing Information,or ask your healthcare provider, or visit MyKybella.com.
CoolSculpting® Treatment Important Information
Uses
CoolSculpting® is FDA-cleared for the treatment of visible fat bulges in the submental (under the chin) and submandibular (under the jawline) areas, thigh, abdomen, and flank, along with bra fat, back fat, underneath the buttocks (also known as banana roll), and upper arm. It is also FDA-cleared to affect the appearance of lax tissue with submental area treatments. CoolSculpting® is not a treatment for weight loss.
Important Safety Information
This procedure is not for everyone. You should not be treated with CoolSculpting® if you suffer from cryoglobulinemia, cold agglutinin disease, or paroxysmal cold hemoglobinuria.
Tell your doctor if you have any medical conditions including recent surgery, pre-existing hernia, and any known sensitivities or allergies.
During the procedure you may experience sensations of pulling, tugging, mild pinching, intense cold, tingling, stinging, aching, and cramping at the treatment site. These sensations lessen as the area becomes numb. Following the procedure, typical side effects include temporary redness, swelling, blanching, bruising, firmness, tingling, stinging, tenderness, cramping, aching, itching, or skin sensitivity, and sensation of fullness in the back of the throat after submental or submandibular area treatment.
Rare side effects may happen in 1 to 10 out of 10,000 CoolSculpting® treatments (between 0.01% to 0.1%). One such rare side effect is a visible enlargement in the treated area which may develop two to five months after treatment, will not resolve on its own, and may require surgical intervention for correction.
Please see full Important Safety Information for CoolSculpting® on CoolSculpting.com
CoolTone® Uses and Important Safety Information
Uses
The CoolTone® device is FDA-cleared for improvement of abdominal tone, strengthening of the abdominal muscles, and development for firmer abdomen. CoolTone® is also FDA-cleared for strengthening, toning, and firming of buttocks and thighs.
Important Safety Information
The CoolTone® procedure is not for everyone. You should not have the CoolTone® treatment in areas with metal, electrical, or electronic implants/devices like cardiac pacemakers, implanted hearing devices, implanted defibrillators, implanted neurostimulators, drug pumps, or hearing aids.
Tell your doctor if you have any medical conditions as CoolTone® should not be used over a menstruating uterus, over areas of the skin that lack normal sensation, in patients with fever, malignant tumor, hemorrhagic conditions, epilepsy, recent surgical procedure, pulmonary insufficiency, or pregnancy.
CoolTone® should be used with caution in patients with Graves’ disease (an autoimmune disorder that causes overactive thyroid), active bleeding disorders, or seizure disorders.
Women who are close to menstruation may find that it comes sooner, or cramping is increased or intensified with CoolTone® treatments, therefore, it is recommended to not undergo treatment during this time of the month.
CoolTone® should not be used in the heart or head areas, areas of new bone growth, over the carotid sinus nerves, or over the neck or mouth. CoolTone® should not be applied over swollen, infected, inflamed areas or skin eruptions. Caution should be used for patients with suspected or diagnosed heart problems.
Common side effects may include, but may not be limited to, muscular pain, temporary muscle spasm, temporary joint or tendon pain, and redness at or near the treatment site.
Ask your Healthcare Provider if CoolTone® is right for you.
Please see full Important Safety Information for additional information at coolsculpting.com/cooltone.
Natrelle® Breast Implants IMPORTANT SAFETY INFORMATION AND APPROVED USES
Breast implants are not considered lifetime devices. The longer people have them, the greater the chances are that they will develop complications, some of which will require more surgery.
Breast implants have been associated with the development of a cancer of the immune system called breast implant–associated anaplastic large cell lymphoma (BIA-ALCL). This cancer occurs more commonly in patients with textured breast implants than smooth implants, although rates are not well defined. Some patients have died from BIA-ALCL.
Patients receiving breast implants have reported a variety of systemic symptoms, such as joint pain, muscle aches, confusion, chronic fatigue, autoimmune diseases, and others. Individual patient risk for developing these symptoms has not been well established. Some patients report complete resolution of symptoms when the implants are removed without replacement.
Who can get breast implants?
Natrelle® Breast Implants are approved for the following:
- Breast augmentation for women at least 22 years old for silicone-filled implants and for women at least 18 years old for saline-filled implants. Breast augmentation includes primary breast augmentation to increase the breast size and revision surgery to correct or improve the result of a primary breast augmentation
- Breast reconstruction. This includes primary breast reconstruction to replace breast tissue that has been removed due to cancer or trauma or that has failed to develop properly due to a severe breast abnormality. This also includes revision surgery to correct or improve the result of a primary breast reconstruction
Who should NOT get breast implants?
Breast implant surgery should NOT be performed in:
- Women with active infection anywhere in their body
- Women with existing cancer or precancer of their breast who have not received adequate treatment for those conditions
- Women who are currently pregnant or nursing
What should I tell my doctor?
Tell your doctor if you have any of the following conditions, as the risks of breast implant surgery may be higher:
- Autoimmune diseases (eg, lupus and scleroderma)
- A weakened immune system (eg, taking medications to decrease the body’s immune response)
- Planned chemotherapy or radiation therapy following breast implant placement
- Conditions or medications that interfere with wound healing and blood clotting
- Reduced blood supply to breast tissue
- Clinical diagnosis of depression or other mental health disorders, including body dysmorphic disorder and eating disorders
- Those with a diagnosis of depression or other mental health disorders should wait for resolution or stabilization of these conditions prior to undergoing breast implantation surgery
What else should I consider?
- There is a Boxed Warning for breast implants. Please see bold text at beginning
- Many changes to your breasts following implantation are irreversible. If you later choose to have your implants removed and not replaced, you may experience dimpling, puckering, wrinkling, or other cosmetic changes, which may be permanent
- Breast implantation is likely not a one-time surgery. The longer implants are in place, the greater the potential risk for complications. You will likely need additional surgeries on your breasts due to complications or unacceptable cosmetic results. Thus, you should also consider the complication rates for later (revision) surgery since you may experience these risks in the future
- Cancer treatments and surgery will affect the outcome and timing of breast reconstruction
- Breast implants may affect your ability to breastfeed, either by reducing or eliminating milk production
- Rupture of a silicone-filled breast implant is most often silent. Even if you have no symptoms, you should have your first ultrasound or MRI at 5 to 6 years after your initial implant surgery and then every 2 to 3 years thereafter regardless of whether your implants are for augmentation or reconstruction. If you have symptoms of or uncertain ultrasound results for breast implant rupture, an MRI is recommended. Additional imaging may be required depending on your medical history and status. The health consequences of a ruptured silicone gel-filled breast implant have not been fully established
- Routine screening mammography for breast cancer will be more difficult, and implants may rupture during the procedure. Perform self-examination every month for cancer screening and ask your surgeon to help you distinguish the implant from your breast tissue. Lumps, persistent pain, swelling, hardening, or changes in implant shape should be reported to your surgeon and possibly evaluated with imaging
What are key complications with breast implants?
Key complications include reoperation, implant removal with or without replacement, implant rupture with silicone-filled implants, implant deflation with saline-filled implants, and capsular contracture (severe scar tissue around the implant). Other complications include breast pain, swelling, asymmetry, wrinkling/rippling, implant malposition nipple complications, hypertrophic scarring, and implant palpability/visibility.
Talk to your doctor about other complications.
For more information, see the patient brochures at www.allergan.com/products.
To report a problem with Natrelle® Breast Implants, please call Allergan® at 1-800-624-4261.
The sale and distribution of Natrelle® Breast Implants is restricted to licensed physicians who provide information to patients about the risks and benefits of breast implant surgery.
REVOLVE™ ADVANCED ADIPOSE SYSTEM
CONSUMER INDICATIONS AND IMPORTANT SAFETY INFORMATION
What is the REVOLVE™ System?
The REVOLVE™ Advanced Adipose System (REVOLVE™ System) is used for aspiration, harvesting, filtering, and transferring of fat for aesthetic body shaping. The REVOLVE™ System is intended for use in the following surgeries when drawing fat is desired: plastic and reconstructive surgery, gastrointestinal and affiliated organ surgery, urological surgery, general surgery, bone or muscle surgery, gynecological surgery, thoracic surgery, and minimally invasive surgery.
IMPORTANT SAFETY INFORMATION
Who should NOT use REVOLVE™ System?
REVOLVE™ System should not be used by your physician if you currently have any disease that adversely affects wound healing, and poor overall health status.
What warnings should I be aware of?
REVOLVE™ System will not, in and of itself, produce significant weight loss. This device should be used by your physician with extreme caution if you have a chronic medical condition such as diabetes, heart, lung, or circulatory system disease, or obesity.
What precautions should I be aware of?
REVOLVE™ System is designed to remove localized deposits of excess fat through a small incision and subsequently transfer the tissue back to you. Use of this device is limited to those physicians who have the appropriate level of medical education and surgical experience in the appropriate surgical procedures. Results of the procedure will vary depending upon your age, surgical site, and experience of the physician. Results of the procedure may or may not be permanent.
What are possible side effects?
Some common adverse effects associated with fat transfer are unevenness, over- and/or under-correction, tissue lumps, bleeding, and scarring. Potential adverse effects associated with REVOLVE™ System include fat cell death, formation of cysts, infection, chronic immune system response, allergic reaction and inflammation.
REVOLVE™ System is available by prescription only.
This information is not intended to replace a discussion with your surgeon. It does not describe all the potential risks associated with fat grafting procedures. Every patient’s situation is different, so please consult with your surgeon to determine if the use of REVOLVE™ System is right for you.
For more information, please see the Instructions for Use (IFU) and User Manual for REVOLVE™ System.
To report an adverse reaction, please call Allergan at 1.800.367.5737.
SkinMedica®
Most of the SkinMedica® products described on this website are intended to meet the FDA’s definition of a cosmetic product, an article applied to the human body to cleanse, beautify, promote attractiveness, and alter appearances. These SkinMedica® products are not intended to be drug products that diagnose, treat, cure, or prevent any disease or condition. These products have not been approved by the FDA, and the statements on these pages have not been evaluated by the FDA.
SkinMedica® Total Defense + Repair Broad Spectrum Sunscreens (SPF 34, SPF 34 Tinted, and SPF 50+) and Essential Defense Broad Spectrum Sunscreens (Everyday Clear SPF 47, Mineral Shield Tinted SPF 32, and Mineral Shield SPF 35) are over-the-counter drug products which are formulated and marketed pursuant to FDA’s governing regulations set forth at 21 C.F.R. Part 352.
SkinMedica® Purifying Foaming Wash is an over-the-counter drug product that are formulated and marketed pursuant to the FDA’s governing regulations set forth at 21 CFR Part 333 Subpart D.
LATISSE® (bimatoprost ophthalmic solution) 0.03% Important Information
Approved Use
LATISSE® is an FDA-approved treatment to grow eyelashes for people with inadequate or not enough lashes.
Important Safety Information
Do not use LATISSE® if you are allergic to one of its ingredients. If you use/used prescription products for eye pressure problems, use LATISSE® under doctor care. May cause brown darkening of the colored part of the eye which is likely permanent. LATISSE® may cause eyelid skin darkening which may be reversible. Only apply at base of upper lashes. DO NOT APPLY to lower lid. Hair may grow outside the treatment area. If you have eye problems/surgery, consult your doctor. Common side effects include itchy and red eyes. If discontinued, lashes gradually return to previous appearance.
These are not all the possible side effects of LATISSE®. For more information, please talk to your doctor.
Please see LATISSE® full Prescribing Information.
DiamondGlow®
Uses
The DiamondGlow® device is a general dermabrasion device that gently removes the top layer of skin and delivers topical cosmetic serums onto the skin.
Important Safety Information
The DiamondGlow® treatment is not for everyone. You should not have a DiamondGlow® treatment if you have compromised skin quality. Tell your provider if you are pregnant or lactating, or if you have any medical conditions, including allergies, and if you are using topical medications on the area to be treated.
Typical side effects include a scratchy, stinging sensation during the treatment and temporary tightness, redness or slight swelling after the treatment. Rare serious side effects may also occur and include severe skin irritation and allergic reactions.
SkinMedica® Pro-Infusion Serums Disclaimer
SkinMedica® Pro-Infusion Serums are intended to meet the FDA’s definition of a cosmetic product, an article applied to the human body to cleanse, beautify, promote attractiveness, and alter appearances. These products are not intended to be drugs that diagnose, treat, cure, or prevent any disease or condition. These products have not been approved by the FDA and the statements have not been evaluated by the FDA.
Ocumend®
Claims for Ocumend® are based on traditional homeopathic practice, not accepted medical evidence. Not FDA evaluated.
Please talk to your provider for additional information.
FAQs
Is OnabotulinumtoxinA the same as Botox? ›
OnabotulinumtoxinA injection (Botox Cosmetic) is used to
temporarily smooth crow's feet lines (wrinkles near the outer corner of the eye) in adults 18 years of age and older, and to temporarily smooth forehead lines in adults 18 years of age and older.
OnabotulinumtoxinA is used to treat increased muscle stiffness in the elbow, wrist, and finger muscles or ankle and toe muscles in adults with upper or lower limb spasticity or in children 2 to 17 years of age with upper and lower limb spasticity.
Is there a difference between Botox and Botox cosmetic? ›First, Both Botox and Botox Cosmetic contain botulinum toxin. The only difference between the two are the conditions that are approved for by the FDA. Botox Cosmetic is approved to treat the face such as the frown lines. Botox is approved to treat spastic disorders.
What is OnabotulinumtoxinA made of? ›OnabotulinumtoxinA is a germ-free medical treatment made from the purified toxin of a bacterium called Clostridium botulinum.
Which is the best Botox to use? ›A comparative study conducted on the content of Botulinum toxin found in Botox®/Vistabel®, Dysport®/Azzalure®, and Xeomin®/Bocouture® showed that Xeomin had the highest neurotoxin activity, then the Dysport followed by Botox which has the lowest specific activity level (Frevert, J.
How many units of Botox do you need for forehead? ›A forehead botox injection can require between 10 to 50 units needed in the forehead depending on the severity of your wrinkles. Allergan, the manufacturer of Botox suggests the amount of units that's recommended in the “five” sites of the forehead is 4 units.
Does blurred vision from Botox go away? ›Answer: If the blurred vision is due to Botox it will resolve in approx 3 months when the Botox wears off. If the blurred vision is due to Botox it will resolve in approx 3 months when the Botox wears off. This is an uncommon side effect of Botox.
Where is onabotulinumtoxinA from? ›[1] It is a neurotoxin produced by the bacterium Clostridium botulinum, an anaerobic, gram-positive, spore-forming rod commonly found on plants, in soil, water and the intestinal tracts of animals. Scott[2] first demonstrated the effectiveness of botulinum toxin type A for the management of strabismus in humans.
What happens if you swallow Botox? ›Answer: Effect of Swallowing Botox
The effect of swallowing botulinum toxin in the miniscule amounts injected for facial muscle adjustments will not have an effect even if it could be absorbed through the digestive or aerodigestive tract.
A single unit of Botox costs around $10 to $15, and an average treatment can include 30 to 40 units, the American Society of Plastic Surgeons (ASPS) reported in 2019. That means a typical treatment can run anywhere from $300 to $600.
How safe is cosmetic Botox? ›
Botox injections are relatively safe when performed by an experienced doctor. Possible side effects and complications include: Pain, swelling or bruising at the injection site. Headache or flu-like symptoms.
Does cosmetic Botox help with headaches? ›What is Botox Therapeutic used for? Botox Therapeutic focuses on relieving multiple pain points, including: Migraines and headaches. Neck pain.
Who should not use Botox? ›Who Should Not Get Botox? People who are pregnant, breastfeeding, or have a neurological disease shouldn't use Botox. Because Botox doesn't work for all wrinkles, check with a doctor first. You shouldn't have Botox shots if you're allergic to cow's milk protein.
How long does Botox stay in your system? ›Answer: Botox in Body
For most patients, botox will stay in your body for 3 - 6 months. For patients who have used the product continually for a long period of time, the duration in the system will increase. An experienced and expert injector will create a natural look.
An upset stomach, nausea, or constipation can occur in 1 to 10% of patients. Symptoms are reported as mild or moderate and typically last a few days up to two weeks.
Which Botox lasts the longest? ›Botulinum toxin injections usually last at least three months. Some people may experience effects that last up to four to five months or longer depending on the area treated and the dose injected. According to some studies, women who received Xeomin for glabellar lines reported longer-lasting effects compared to Botox.
How do you make Botox last longer? ›If you have treatments at regular intervals, then your muscles will become weaker over time. This means that the effects will last longer. Try to avoid the sun, especially on the day of treatment. Sun exposure boosts blood circulation, causing blood vessels to dilate, potentially dispersing Botox faster than normal.
What's better than Botox for wrinkles? ›Dysport is more diluted than Botox. The difference in concentration typically occurs because Dysport uses smaller protein molecules to induce muscle relaxation. These smaller proteins are less likely to be broken down by antibodies, making the results of Dysport injections quite desirable for patients.
How many units of Botox is good for first time users? ›Your First Time
Most patients receive just one or two units per injection site spacing them around the desired area.
- Do Not Drink Wine for One Week Before Your Appointment. ...
- Don't Take Anti-Inflammatory Medications During the Week Before BOTOX. ...
- Avoid Foods That Contain Garlic (and Consider Using Arnica) ...
- Save the Workout. ...
- Wait to Apply Makeup. ...
- Use a Gentle Facial Cleanser.
How can you tell if someone had Botox? ›
“When an area of the face is frozen with absolutely no wrinkles, you can assume the person has had a date with a needle.” "When you look at a photo and see an area of the face that is extremely smooth and shiny," Rusher says, "that can be an indicator that the person may have had Botox."
How long does it take for eyelid to droop after Botox? ›In most cases, droopy eyelid occurs between one and three weeks after treatment, and patients typically experience this adverse effect for just a few weeks. According to Dr. Holman, “It's important to remember that, like Botox treatments, a drooping eyelid is usually temporary. The effect will wear off after a while.
How long does droopy eyelid last after Botox? ›Botox is a temporary treatment. The treatment can last three to seven months, but the droopy eyelids will typically go away in four to six weeks.
Can Botox affect your brain? ›Although there have been recent lawsuits in the media attempting to link Botox to brain damage, there's no concrete evidence to suggest that Botox actually causes brain damage.
Can Botox cause nerve damage? ›Abstract. The therapeutic use of botulinum toxin (Botox) is increasing in popularity. Previous studies have shown that various drugs, especially when injected intrafascicularly, can cause major nerve damage.
Can Botox cause Stroke? ›Botox will not cause a stroke. Systemic symptoms reported with medical uses of high doses of Botox (in sick children with CP) have been difficulty swallowing or breathing.
Can Botox cause permanent paralysis? ›Over time, if Botox is injected repeatedly into the same area of the body, it may cause permanent paralysis of the muscle.
Can Botox cause heart problems? ›The research shows that having facial Botox injections for cosmetic reasons can also produce side-effects including muscle stiffness, pain, dizziness and even a heart attack.
Does Botox cause hair loss? ›Botulinum toxin A can increase blood flow to the follicle, thus stimulating hair growth. However, in patients repeatedly treated for forehead wrinkles, it can induce hair loss.
Does Botox harm the liver? ›Answer: Botox not harmful to liver or kidneys
It is designed not to travel systemically. The quantity of Botox even if it does get into the blood stream is very small. As of this writing, the drug has been used millions of times without reports of kidney or liver damage.
How long does Botox last the first time? ›
You can expect that your Botox treatment to last up to six months after your first treatment. Around month three or four, you can expect to have some movement back. You are likely to see the maximum results of your first treatment from seven days to three to four months after.
Is 20 units of Botox a lot? ›How much Botox is permissible on the forehead? Botox comes in dosages between 50 and 100 units per vial. Some practitioners say they inject an average of 10 to 30 units into the forehead. Allergan, the manufacturer of Botox Cosmetic, suggests a dosage of 4 units each in five sites on the forehead, totaling 20 units.
How much is Botox for 11 lines? ›How much is Botox for 11 lines? Depending on the number of units, Botox for 11 lines can consist of 15-40 units of injection with each injection ranging from $8-$15 per unit depending on location and physician. These Botox injections can range from a total price of $200 to $1,500 for 11 lines.
What happens after years of Botox? ›Over time, repeated injections of Botox® to a particular area in the body can also cause permanent paralysis of the muscle. This is by far one of the most important and dangerous side effects of using Botox® injections. The toxins can spread into the surrounding tissues and this can prove to be fatal.
What age should you start Botox? ›If you want to prevent the earliest fine lines from becoming full-blown wrinkles, preventative Botox can be the solution. Botox is approved for patients who are 18 years and older and most experts agree that patients in their mid to late 20s and early 30s are at a good age for preventative Botox treatment.
What should I avoid after Botox? ›Don't lie down for at least 3 hours after receiving Botox. Don't go into any saunas, hot tubs, or tanning booths for at least 4 hours. This helps to prevent bruising, because heat can raise your blood pressure. Otherwise, you can resume your regular activities right after getting Botox.
Can Botox cause chronic fatigue? ›Botulism can occur hours, days, or even weeks after a Botox injection. Symptoms may include: fatigue (lack of energy) trouble breathing.
Can you get just a little Botox? ›Baby Botox is a fantastic option for those who are just starting out with Botox or who want a more natural-looking result. If you have shallow lines or want to prevent wrinkles down the line, it could be the perfect procedure for you. The downtime is limited, and you don't need to do much to prepare or recover.
How long does it take for Botox to work? ›Getting Botox takes only a few minutes and doesn't require anesthesia. Botox is injected with a fine needle into specific muscles with only minor discomfort. It generally takes three to seven days to take full effect, and it is best to avoid alcohol starting at least one week before the procedure.
What are the 3 common side effects of Botox? ›Serious adverse effects after cosmetic use of botulinum toxin include dysphagia, muscle weakness, and allergic reactions [22, 23]. Dysphagia and muscle weakness are common symptoms of botulism.
Why you should avoid Botox? ›
"If you do too much Botox on your forehead for many, many years, the muscles will get weaker and flatter," cautions Wexler, adding that the skin can also appear thinner and looser. Moreover, as your muscles become weaker, they can start to recruit surrounding muscles when you make facial expressions.
Does Botox make you look older? ›Will it cause you to look older? From a medical point of view, once the effects of Botox wear off, your face will NOT look older. Actually the opposite happens with certainty. Botox injections help you get rid of some of the unwanted wrinkles around the eyes, forehead, chin etc….
What happens if Botox hits a vein? ›If the Botox injection is allowed to pierce a vein and travel to other areas of the face, partial temporary paralysis may be the result. Some patients have experienced difficulty with speech or freezing of facial muscles after a Botox injection was erroneously allowed to migrate to other parts of the face.
How long after Botox can you shower? ›Why Do You Need To Avoid It? The risk of bruising following Botox is increased when the body or face gets too hot. In addition to avoiding hot tubs, saunas, and other similar places, do not take a hot bath or shower for at least 24 hours after having this treatment.
Can you drink coffee before Botox? ›You should also avoid coffee before Botox. This is because coffee contains caffeine, which may trigger your blood pressure and increase the likelihood of bruising during the procedure. For this reason, you should avoid coffee and other beverages containing caffeine at least 24 hours before the treatment.
Why do eyes feel weird after Botox? ›Spread of Botox can cause changes in vision. This can include double vision, blurred vision, dry eyes, excessive tearing and drooping of the eyelid. If experiencing these symptoms, consult your doctor.
Why do I feel sick after Botox? ›Redness, bruising, infection, and pain at the injection site may occur. Dizziness, mild difficulty swallowing, respiratory infections such as cold or flu, pain, nausea, headache, and muscle weakness may occur when this medication is used to relax muscles.
How should I sleep after Botox? ›Don't sleep where you've had Botox injected for one night
Sleeping on your back is important because the Botox injections need time to settle into your muscles. Yes, laying on your face could prevent the injections from settling in and lead to you having less than perfect results.
Generic Name: onabotulinumtoxinA
Botulinum toxin is used to treat certain eye disorders such as crossed eyes (strabismus) and uncontrolled blinking (blepharospasm), to treat muscle stiffness/spasms or movement disorders (such as cervical dystonia, torticollis), and to reduce the cosmetic appearance of wrinkles.
Unfortunately, there are no generic versions of Xeomin or Botox available.
Where is onabotulinumtoxinA from? ›
[1] It is a neurotoxin produced by the bacterium Clostridium botulinum, an anaerobic, gram-positive, spore-forming rod commonly found on plants, in soil, water and the intestinal tracts of animals. Scott[2] first demonstrated the effectiveness of botulinum toxin type A for the management of strabismus in humans.
How do you say onabotulinumtoxinA? ›How to pronounce onabotulinumtoxinA (Memorizing ...
Who should not use Botox? ›Who Should Not Get Botox? People who are pregnant, breastfeeding, or have a neurological disease shouldn't use Botox. Because Botox doesn't work for all wrinkles, check with a doctor first. You shouldn't have Botox shots if you're allergic to cow's milk protein.
What should I avoid after Botox? ›Don't lie down for at least 3 hours after receiving Botox. Don't go into any saunas, hot tubs, or tanning booths for at least 4 hours. This helps to prevent bruising, because heat can raise your blood pressure. Otherwise, you can resume your regular activities right after getting Botox.
What are the risks of Botox? ›...
Call your doctor right away if you notice any of these effects hours to weeks after receiving Botox:
- Muscle weakness.
- Vision problems.
- Trouble speaking or swallowing.
- Breathing problems.
- Loss of bladder control.
A New Generation of Long-Lasting Neurotoxins
While Botox and Dysport can last up to four months, Revance Therapeutics' wrinkle-reducing injection claims to diminish wrinkles for up to six months. Comprised of botulinum toxin type A, Revance's RT002 is currently in clinical trials and hopes to enter the market in 2020.
Dysport is more diluted than Botox. The difference in concentration typically occurs because Dysport uses smaller protein molecules to induce muscle relaxation. These smaller proteins are less likely to be broken down by antibodies, making the results of Dysport injections quite desirable for patients.
What is the cheaper brand of Botox? ›Sometimes called “Newtox” (or #newtox), Jeuveau is very similar to Botox, which has been the gold standard of wrinkle relaxers for almost two decades. Like Botox, Jeuveau is also derived from a botulinum toxin that is injected in safe, small doses into facial muscles.
Can Botox cause nerve damage? ›Abstract. The therapeutic use of botulinum toxin (Botox) is increasing in popularity. Previous studies have shown that various drugs, especially when injected intrafascicularly, can cause major nerve damage.
Can Botox cause Stroke? ›Botox will not cause a stroke. Systemic symptoms reported with medical uses of high doses of Botox (in sick children with CP) have been difficulty swallowing or breathing.
Can Botox cause neurological problems? ›
FDA has reported adverse events after BoNT injection affecting nervous system far from initial site of injection such as speech disorder, nystagmus, restless leg syndrome, and even coma. Central nervous system involvement included 23.5% of serious and 24.9% of non-serious events (1).
What happens if you swallow Botox? ›Answer: Effect of Swallowing Botox
The effect of swallowing botulinum toxin in the miniscule amounts injected for facial muscle adjustments will not have an effect even if it could be absorbed through the digestive or aerodigestive tract.
Botox is a toxin produced by bacteria. It belongs to a class of drugs called neurotoxins, which relax muscles by decreasing nerve signals to those muscles.
What color is Botox? ›Answer: Color of Botox
Botox when reconstituted as directed by Allergan is clear. It is sold freeze dried in small vials as a whitish powder, and is reconstituted into a solution by the physician before injection.